UJI AKTIVITAS EKSTRAK DAUN KARET KERBAU (Ficus elastica Roxb. Ex Hornem) SEBAGAI ANTI HIPERKOLESTEROLEMIA PADA TIKUS PUTIH JANTAN (Rattus norvegicus) GALUR SPRAGUE DAWLEY

Afridah Nasution, Meri and Moerfiah and Ramani, Sofyan (2020) UJI AKTIVITAS EKSTRAK DAUN KARET KERBAU (Ficus elastica Roxb. Ex Hornem) SEBAGAI ANTI HIPERKOLESTEROLEMIA PADA TIKUS PUTIH JANTAN (Rattus norvegicus) GALUR SPRAGUE DAWLEY. Skripsi thesis, Universitas Pakuan.

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Abstract

ABSTRACT Hypercholesterolemia is a major risk factor for the development of atherosclerosis. To be able to lower total cholesterol levels, anti hypercholesterolemia is needed. One of the plants that can lower cholesterol levels in the blood is buffalo rubber leaves (Ficus elastica Roxb. Ex Hornem) because they contain flavonoids and steroids. The purpose of this study was to determine the activity and use of buffalo rubber leaf extract dosages which are effective as anti hypercholesterolemia, using a Factorial Factor Random Block Design. This is the dose of P1(100mg / KgBB); P2 (200mg / KgBB); P3 (300 mg / KgBB) negative control (K-) and positive control (K +) with 5 repetitions. The results showed that giving buffalo rubber leaf extract could reduce total cholesterol levels, so that it has anti hypercholesterolemic activity in male white rats. The optimum interaction between dosage and length of time for giving buffalo rubber leaf extract as anti hypercholesterolemia is a dosage of 300mg / KgBW with a duration of 15 days. Keywords: Hypercholesterolemia, Buffalo Rubber, Male White Rats

Item Type: Thesis (Skripsi)
Subjects: Fakultas Ilmu Pengetahuan Alam dan Matematika > Biologi
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam > Biologi
Depositing User: PERPUSTAKAAN FAKULTAS MATEMATIKA DAN ILMU PENGETAHUAN ALAM UNPAK
Date Deposited: 26 Aug 2022 11:29
Last Modified: 03 Sep 2022 18:01
URI: http://eprints.unpak.ac.id/id/eprint/996

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