<> "The repository administrator has not yet configured an RDF license."^^ . <> . . . "EFFECTIVENESS TEST LEAF EXTRACT COMBINATION Noni (Morinda citrifolia L.) \r\nEXTRACT SKIN FRUIT AND WATERMELON (Citrullus lanatus L.) ON BLOOD \r\nGLUCOSE LEVELS AND WHITE MALE MICE"^^ . "ABSTRACT\r\nDiabetes Mellitus (DM) is one of the a type of chronic metabolic disorder characterized by \r\nblood glucose levels that exceed normal values. This study aims to determine the effectiveness of \r\nthe combined dose of noni leaf extract and watermelon rind extract as a reduction in blood sugar \r\nlevels in male white mice. As many as 35 test animals were used, which were divided into 7 \r\nexperimental groups with each treatment consisting of 5 mice as replications. The treatment group \r\nconsisted of: positive control (glibenclamide 0.65 mg / 20 g BW), negative control (CMC Na), \r\ndose 1 (noni leaf extract 32 mg / 20 g BW), dose 2 (watermelon rind extract 14 mg / 20 g BW), \r\ncombination dose 3 (noni leaf extract 32 mg / 20 g BW : watermelon rind extract 14 mg / 20 g \r\nBW), combination dose 4 (noni leaf extract 32 mg / 20 g BW: watermelon rind extract 28 mg / 20 \r\ng BW), a combination dose of 5 (noni leaf extract 16 mg / 20 g BW: watermelon rind extract 28 \r\nmg / 20 g BW), then the test animals measured their blood sugar levels. The data obtained were \r\nthen analyzed using a factorial randomized block design (RBD). Mice were treated according to \r\nthe treatment group for 21 days until the blood sugar levels of the mice were normal, measurement \r\nof blood sugar levels was carried out on days 7, 14 and 21. The results showed that all treatment \r\ndoses had activity to lower blood sugar levels. The combination of noni leaf extract at a dose of 32 \r\nmg / 20 gBB and watermelon rind extract 14 mg / 20 gBB with a duration of administration for 14 \r\ndays is the most effective dose as a reduction in blood sugar levels with a percentage reduction of \r\n61.57%.\r\nKey words: Diabetes Mellitus, Antidiabetic, Noni Leaf and Watermelon Rind."^^ . "2021-01" . . "Universitas Pakuan"^^ . . . "Farmasi, Universitas Pakuan"^^ . . . . . . . . . . . . . . . . . "Lusi"^^ . "Agus Setiani"^^ . "Lusi Agus Setiani"^^ . . "E, Mulyati"^^ . "Effendi"^^ . "E, Mulyati Effendi"^^ . . "Aprina"^^ . "Septian Dewi"^^ . "Aprina Septian Dewi"^^ . . "Universitas Pakuan"^^ . . . "Fakultas MIPA"^^ . . . "Farmasi"^^ . . . . . . "HTML Summary of #1419 \n\nEFFECTIVENESS TEST LEAF EXTRACT COMBINATION Noni (Morinda citrifolia L.) \nEXTRACT SKIN FRUIT AND WATERMELON (Citrullus lanatus L.) ON BLOOD \nGLUCOSE LEVELS AND WHITE MALE MICE\n\n" . "text/html" . . . "Ilmu Komputer"@en . .