TY  - THES
Y1  - 2020/07//
AV  - none
UR  - http://eprints.unpak.ac.id/637/
A1  - Naufal Salsabila, Bunga
A1  - Effendi MS, Mulyati
A1  - Nurmala, Sara
ID  - eprintsunpak637
N2  - ABSTRACT
Stimulance is a compound that affects the Central Nervous System (CNS), can increase 
concentration and stimulate the CNS to eliminate fatigue. Caffeine is one of the main agents 
that can be used as a stimulant. Rambutan leaves contain flavonoids which can be an 
alternative as a stimulant. This study used 25 male mice which were divided into 5 groups, 
namely the Negative Control group (CMC Na 0.5%), Positive Control (Caffeine 0.52 g / 20 g 
BW), Dose I (25 mg / KgBB), Dose II (50mg / KgBB), and Dose III (100 mg / KgBB) each 
group consisted of 5 mice, orally orally by gastric sonde. The results of the study prove that 
96% ethanol extract of rambutan leaves is significant as a stimulant enhancer (p <0.05). The 
negative group had an average survival time of mice as low as 1.6 seconds, positive groups 
had an average of 140.8 seconds. The most effective dose is Dose III (100 mg / KgBB) as an 
increase in stimulants equivalent to Positive Control (Caffeine 0.52 mg / 20 g BW) with an 
average value of mice remaining in rotarod for 128.4 seconds.Keywords: Rambutan Leaves, 
Stimulance, Mice and Rotarod
M1  - Skripsi
TI  - UJI EFEKTIVITAS STIMULANSIA EKSTRAK ETANOL 96% DAUN RAMBUTAN 
(Nephelium lappaceum L.) PADA MENCIT PUTIH (Mus musculus L)
PB  - Universtas Pakuan
ER  -