eprintid: 637
rev_number: 9
eprint_status: archive
userid: 46
dir: disk0/00/00/06/37
datestamp: 2022-08-25 11:59:26
lastmod: 2022-09-03 16:16:01
status_changed: 2022-08-25 11:59:26
type: thesis
metadata_visibility: show
creators_name: Naufal Salsabila, Bunga
creators_name: Effendi MS, Mulyati
creators_name: Nurmala, Sara
creators_NPM: 066115157
creators_id: salsabilanbunga98@gmail.com
contributors_type: http://www.loc.gov/loc.terms/relators/THS
contributors_type: http://www.loc.gov/loc.terms/relators/THS
contributors_name: Effendi MS, Mulyati
contributors_name: Nurmala, Sara
contributors_NIDN: 0025105702
contributors_NIDN: 0421018703
corp_creators: Universitas Pakuan
corp_creators: Fakultas MIPA
corp_creators: Farmasi
title: UJI EFEKTIVITAS STIMULANSIA EKSTRAK ETANOL 96% DAUN RAMBUTAN 
(Nephelium lappaceum L.) PADA MENCIT PUTIH (Mus musculus L)
ispublished: pub
subjects: QL
divisions: sch_che
full_text_status: none
abstract: ABSTRACT
Stimulance is a compound that affects the Central Nervous System (CNS), can increase 
concentration and stimulate the CNS to eliminate fatigue. Caffeine is one of the main agents 
that can be used as a stimulant. Rambutan leaves contain flavonoids which can be an 
alternative as a stimulant. This study used 25 male mice which were divided into 5 groups, 
namely the Negative Control group (CMC Na 0.5%), Positive Control (Caffeine 0.52 g / 20 g 
BW), Dose I (25 mg / KgBB), Dose II (50mg / KgBB), and Dose III (100 mg / KgBB) each 
group consisted of 5 mice, orally orally by gastric sonde. The results of the study prove that 
96% ethanol extract of rambutan leaves is significant as a stimulant enhancer (p <0.05). The 
negative group had an average survival time of mice as low as 1.6 seconds, positive groups 
had an average of 140.8 seconds. The most effective dose is Dose III (100 mg / KgBB) as an 
increase in stimulants equivalent to Positive Control (Caffeine 0.52 mg / 20 g BW) with an 
average value of mice remaining in rotarod for 128.4 seconds.Keywords: Rambutan Leaves, 
Stimulance, Mice and Rotarod
date: 2020-07
date_type: published
institution: Universtas Pakuan
department: Farmasi
thesis_type: Skripsi
thesis_name: Sarjana
citation:   Naufal Salsabila, Bunga and Effendi MS, Mulyati and Nurmala, Sara  (2020) UJI EFEKTIVITAS STIMULANSIA EKSTRAK ETANOL 96% DAUN RAMBUTAN (Nephelium lappaceum L.) PADA MENCIT PUTIH (Mus musculus L).  Skripsi thesis, Universtas Pakuan.