eprintid: 996
rev_number: 9
eprint_status: archive
userid: 46
dir: disk0/00/00/09/96
datestamp: 2022-08-26 11:29:12
lastmod: 2022-09-03 18:01:40
status_changed: 2022-08-26 11:29:12
type: thesis
metadata_visibility: show
creators_name: Afridah Nasution, Meri
creators_name: , Moerfiah
creators_name: Ramani, Sofyan
creators_NPM: 061115008
creators_id: nasutionmeri@gmail.com
contributors_type: http://www.loc.gov/loc.terms/relators/THS
contributors_type: http://www.loc.gov/loc.terms/relators/THS
contributors_name: , Moerfiah
contributors_name: Ramani, Sofyan
contributors_NIDN: 0427045901
corp_creators: Universitas Pakuan
corp_creators: Fakultas MIPA
corp_creators: Biologi
title: UJI AKTIVITAS EKSTRAK DAUN KARET KERBAU (Ficus elastica Roxb. 
Ex Hornem) SEBAGAI ANTI HIPERKOLESTEROLEMIA PADA TIKUS 
PUTIH JANTAN (Rattus norvegicus) GALUR SPRAGUE DAWLEY
ispublished: pub
subjects: QP
divisions: sch_civ
full_text_status: none
abstract: ABSTRACT
Hypercholesterolemia is a major risk factor for the development of atherosclerosis. To 
be able to lower total cholesterol levels, anti hypercholesterolemia is needed. One of 
the plants that can lower cholesterol levels in the blood is buffalo rubber leaves (Ficus 
elastica Roxb. Ex Hornem) because they contain flavonoids and steroids. The purpose 
of this study was to determine the activity and use of buffalo rubber leaf extract dosages 
which are effective as anti hypercholesterolemia, using a Factorial Factor Random 
Block Design. This is the dose of P1(100mg / KgBB); P2 (200mg / KgBB); P3 (300 
mg / KgBB) negative control (K-) and positive control (K +) with 5 repetitions. The 
results showed that giving buffalo rubber leaf extract could reduce total cholesterol 
levels, so that it has anti hypercholesterolemic activity in male white rats. The optimum 
interaction between dosage and length of time for giving buffalo rubber leaf extract as 
anti hypercholesterolemia is a dosage of 300mg / KgBW with a duration of 15 days.
Keywords: Hypercholesterolemia, Buffalo Rubber, Male White Rats
date: 2020-11
date_type: published
institution: Universitas Pakuan
department: Biologi
thesis_type: Skripsi
thesis_name: Sarjana
citation:   Afridah Nasution, Meri and Moerfiah and Ramani, Sofyan  (2020) UJI AKTIVITAS EKSTRAK DAUN KARET KERBAU (Ficus elastica Roxb. Ex Hornem) SEBAGAI ANTI HIPERKOLESTEROLEMIA PADA TIKUS PUTIH JANTAN (Rattus norvegicus) GALUR SPRAGUE DAWLEY.  Skripsi thesis, Universitas Pakuan.